Preparing your body for conception can mean a lot of things. It can take anywhere from a year to a few months. The first step I always recommend is to get a thorough assessment done through bloodwork. This is an important step to check for nutritional deficiencies, metabolic disorders, hormonal imbalances, or any other disorders that might come up, causing a barrier to conception.
I also like to go through a few tests like the CBC (Complete Blood Count), which measures your iron stores, vitamin B 12, and vitamin D. The next step is getting a full thyroid panel, specifically TSH, which is your thyroid stimulating hormone. This is an important test to see if any underlying autoimmune thyroid conditions could be a barrier to conception.
The next test on the list is getting a proper blood test for estrogen, progesterone and testosterone. Estrogen is essential not only when preparing for conception but also for carrying the pregnancy to term. Progesterone levels give us an insight into whether or not you ovulate. Testosterone levels can be elevated in certain hormonal imbalances like PCOS, where we often see elevated androgens. Androgens like testosterone can cause symptoms like excess hair growth on the face, acne and hair loss.
Next, we have LH and FSH. LH is the luteinising hormone, and FSH is called the follicle-stimulating hormone. These two levels tell us about egg health, ovarian health and your egg reserve. LH is two, sometimes three times higher than FSH in certain conditions, causing PCOS. And in reverse, if FSH is two or three times higher than LH, we see potential for premature ovarian ageing or premature ovarian failure, which is also a barrier to conception.
Next, we have fasting insulin and fasting glucose. Combined, these can give us an insight into metabolic disorders and insulin resistance, often seen with hormonal imbalances.
Lastly, MH. The anti-mullerian hormone is tested in fertility clinics but is often left out of the preconception testing. Women need to consider whether or not they should get the test, especially if they have a family history of early menopause or premature ovarian failure.
If you have a family history of autoimmune disorders or inflammatory conditions, and something like inflammatory markers, like CRP or AMA, it might be beneficial to include it in this preconception test.